REVIVE MD x DR. ADEEL KHAN - THE LONGEVITY COLLECTION

Your cells age before you do

A physician-designed protocol targeting the three biological systems that drive aging at the cellular level. The products. One system. Every dose backed by published research.

Shop the protocol Read the science

Three products. One complete system.

Each product was designed to address a different node of cellular aging. They are independently effective. Together, they are comprehensive.

Mitochondrial Renewal Longevity Core

Clear. Build. Protect.

Longevity Core

The first all-in-one mitochondrial renewal formula that addresses cellular aging across three biological priorities: clearing damaged mitochondria, building new ones, and protecting the NAD+ and stress response systems they depend on. Six clinically dosed ingredients. No proprietary blends.

  • Supports all-day energy
  • Helps you wake up rested
  • Supports faster recovery
  • Helps maintain mental sharpness
  • Fewer energy dips daily
  • Supports cellular energy production
  • Helps your body keep up
INGREDIENTS
Urolithin A
Urolithin A 600mg
CoQ10
CoQ10 100mg
PQQ
PQQ 15mg
Apigenin
Apigenin 50mg
Rhodiola
Rhodiola 200mg
BioPerine
BioPerine 10mg
NAD+ RESTORATION Longevity Restore

Produce. Preserve. Activate.

Longevity Restore

Most NAD+ supplements stop at production. RESTORE addresses the full NAD+ lifecycle: producing it (NMN), preserving it from CD38-driven destruction (Apigenin), activating the repair pathways it fuels (Pterostilbene/SIRT1), protecting methylation (TMG), clearing senescent cells (Quercetin), inducing autophagy (Spermidine) and defending high-demand tissues (Ergothioneine).

  • Supports clearer thinking
  • Supports healthy metabolism
  • Helps stabilize mood and energy
  • Promotes cellular resilience
  • Helps maintain focus
  • Promotes cellular repair
  • Supports how you feel daily
INGREDIENTS
NMN
NMN 250mg
Euercetin
Euercetin
L-Ergothioneine
L-Ergothioneine
Pterostilbene
Pterostilbene 100mg
Spermidine
Spermidine
TMG
TMG
Apigenin
Apigenin
Performance & Muscle Creatine HMB

Build. Load. Protect.

Creatine HMB

Cellular longevity without physical performance is incomplete. Creatine HMB addresses the third dimension: muscle. Clinical-dose creatine monohydrate for power and lean mass. Clinical-dose HMB to reduce muscle protein breakdown. GAA for dual-pathway creatine loading that standard creatine cannot match. The most studied performance stack in sports nutrition, engineered into one formula.

  • Supports strength and power
  • Helps faster recovery
  • Promotes better performance
  • Helps reduce muscle breakdown
  • Helps preserve muscle mass
  • Helps maintain lean muscle
  • Supports muscle responsiveness
INGREDIENTS
Creatine
Creatine 5g
HMB
HMB 3g
Betaine
Betaine
GAA
GAA 2g
Taurine
Taurine

How they work together

Each product targets a different node of cellular aging. They do not overlap. They compound. Here is how a complete daily protocol looks.

MORNING

Longevity Core

3 capsules with food. Supports mitochondrial renewal and NAD+ protection throughout the day.

MORNING

Longevity Restore

Take alongside Core. Supports NAD+ production, sirtuin activation, and cellular cleanup processes.*

MORNING

Creatine HMB

Mix with water or juice. Supports muscle performance, creatine loading, and muscle integrity during training.

CoQ10 + BioPerine

Core

CoQ10 + BioPerine

ATP production

BioPerine improves CoQ10 bioavailability by ~30%
Urolithin A

Core

Urolithin A

Mitophagy support

Cleared mitochondria free cellular resources for new biogenesis (PQQ)
NMN

Restore

NMN

NAD+ pool

Fuels the sirtuin pathways activated by Pterostilbene
Apigenin

Core + Restore

Apigenin

NAD+ preservation

Protects NAD+ from CD38-driven destruction in both formulas
Creatine + GAA

HMB

Creatine + GAA

Dual-pathway creatine loading

GAA uses a separate transporter, bypassing the creatine transporter ceiling
Dr. Adeel Khan
"The research on mitochondrial aging is no longer speculative. The question is no longer whether these mechanisms matter. It's whether the products on the market are actually addressing them at meaningful doses."

Dr. Adeel Khan

MD

Why a physician was involved

Longevity supplements are everywhere. Clinically honest ones are not. Most products are built backwards, starting with a marketing angle, working backwards to an ingredient list, and stopping short of the doses that the actual research used.

This collection was different. Every formula began with the published science: what breaks down with age, by which mechanism, at what rate, and what the highest-quality evidence suggests about intervention. Then we asked: what is the minimum number of ingredients, at exactly the right doses, to address all of it?

3 products

Each one designed to address a different layer of cellular aging. Together, they cover the full picture: from the power plants inside your cells, to the fuel that runs them, to the machinery that keeps your muscles performing at any age.

Aging does not start with how you look.

It starts inside your mitochondria. In the coenzymes that run your DNA repair systems. In the muscle fibers that begin to lose their ability to rebuild. By the time you notice surface changes, these processes have been underway for years. The window to intervene is earlier than most people think.

Mitochondrial quality control starts to slow. NAD+ levels begin their decades-long decline. Muscle protein synthesis becomes less efficient. Most people feel nothing yet.

The silent decline begins

Recovery takes longer. Energy is less reliable. CoQ10 production drops measurably. Damaged mitochondria accumulate faster than they are cleaned. The compounding begins.

Energy becomes visible

NAD+ is now roughly half of youthful levels. Senescent cells accumulate. Muscle mass decline (sarcopenia) accelerates without active intervention.

Cellular infrastructure strains

Every system that relied on healthy mitochondria, adequate NAD+, and functional muscle begins to show the cumulative cost. The upstream interventions matter most.

Downstream effects compound

Independent Science. No industry-funded.

The studies referenced for this protocol include academic research from the NIH, University of Oslo, Swansea University, and others, conducted independently of the supplement industry. The citations exist. You can verify them.

NATURE NEUROSCIENCE, 2019 — FANG ET AL. (NIH / UNIV. OF OSLO)

Urolithin A activated mitophagy through both PINK1/Parkin-dependent and independent pathways in Alzheimer's models

Urolithin A activated mitophagy through both PINK1/Parkin-dependent and independent pathways in Alzheimer's models

Demonstrated reversal of cognitive deficits across C. elegans and mouse models. No industry funding. Conducted by University of Oslo and the National Institute on Aging.

GEROSCIENCE, 2022 — MULTICENTER RCT

NMN elevated blood NAD+ in a dose-dependent manner across 80 middle-aged adults over 60 days

NMN elevated blood NAD+ in a dose-dependent manner across 80 middle-aged adults over 60 days

300, 600, and 900 mg groups all showed significant NAD+ elevation. Walking endurance and subjective health scores improved across groups.

JISSN POSITION STAND, 2017 — ISSN

Creatine monohydrate is the most effective ergogenic nutritional supplement available for increasing high-intensity exercise capacity and lean body mass

Creatine monohydrate is the most effective ergogenic nutritional supplement available for increasing high-intensity exercise capacity and lean body mass

Position statement from the International Society of Sports Nutrition, representing the consensus of 500+ peer-reviewed studies across 30 years.

JISSN POSITION STAND, 2013 — ISSN ON HMB

HMB at 3g/day attenuates exercise-induced skeletal muscle damage and supports recovery during hard training phases.

HMB at 3g/day attenuates exercise-induced skeletal muscle damage and supports recovery during hard training phases.

Particularly effective during periods of high muscle stress, caloric deficits, overreaching training phases, and in individuals new to resistance training.

What you need to know

Do I need to take all three products together?
No — each product works independently. Longevity Core addresses mitochondrial renewal and NAD+ protection. Longevity Restore supports NAD+ production and sirtuin activation. Creatine HMB targets muscle performance and recovery. You can start with one and add others over time. That said, the protocol was designed as a system. The products do not overlap, and together they address the full picture of cellular aging more completely than any one product alone.
When will I notice something?
Most people notice changes in energy and recovery within 2–4 weeks. Sleep quality improvements are often reported early, typically within the first two weeks. The deeper cellular work — mitochondrial renewal, NAD+ restoration, muscle preservation — operates over a longer timeline. The research behind these ingredients was conducted over 60–90 day periods. Think of the first month as the foundation, not the finish line.
Why do these doses matter - can't I buy a cheaper version with less?
Yes, you can. And most products on the market do exactly that. The problem is that the published research used specific doses — and those are the doses we formulated around. A product with 50mg of NMN instead of 300mg is not a less expensive version of the same thing. It is a different product that borrows the name of an ingredient without delivering the intervention the studies actually tested. Underdosing is how the supplement industry keeps costs down while maintaining the appearance of science.
Can I take these with my existing supplements?
In most cases, yes. These products were designed to work as a standalone protocol, but they do not contain ingredients that commonly conflict with standard supplements. If you are taking medications or have a specific health condition, we recommend reviewing the full ingredient list with your physician before starting. The formulas are free of proprietary blends, so you can see exactly what you are taking and at what dose.
Is this only for older people?
No. Mitochondrial decline begins in your 30s, and NAD+ levels start dropping before most people notice any symptoms. The research suggests that intervening earlier — before the cumulative effects become visible — is more effective than trying to reverse damage after it has compounded. If you are 35 and performing at a high level, this protocol supports the systems that keep you performing. If you are 55 and noticing the effects of time, it addresses the upstream causes.