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Longevity Restore

NAD+ production is step one. There are six more.

$99.99
  • GMP CERTIFIED
  • THIRD-PARTY TESTED
  • PHYSICIAN FORMULATED

Why This Matters?

Rather than relying on unverified claims or hidden blends, Revive MD prioritizes evidence-based formulation, full label transparency, and third-party testing for every batch produced. Our products are formulated with clinically supported ingredients and tested by independent laboratories to confirm exact dosing, quality, and purity.

Clinically Studied Ingredients

Every ingredient in our formulas is selected because it’s supported by human research and traditional use, not hype or trends. You get meaningful nutrients, precise dosing, and thoughtful formulation for real health outcomes.

Transparent Dosing — No Proprietary Blends

Unlike many brands that hide doses in “proprietary blends,” Revive MD puts every ingredient and amount on the label. You know exactly what you take and why it’s included.

Third‑Party Tested for Purity & Accuracy

Unlike many brands that hide doses in “proprietary blends,” Revive MD puts every ingredient and amount on the label. You know exactly what you take and why it’s included.
  • Supports healthy NAD* levels for cellular vitality
  • Promotes recovery and whole-body resilience
  • Promotes cellular energy production
  • Formulated for foundational longevity support

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Longevity Restore
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Should I take Longevity Core or Longevity RESTORE first?

Both. Each addresses different biological mechanisms. They are designed to work together.

How long until I notice a difference?

Most NAD+ trials show measurable blood NAD+ elevation within 2 weeks and functional
improvements within 4 to 12 weeks of consistent daily use.

Why do both Core and RESTORE contain Apigenin?

CD38 modulation is relevant to both formulas. Core preserves the NAD+ that already exists.
RESTORE preserves the NAD+ that NMN is producing. Same ingredient, same dose, different
purpose in each system.

Why is TMG included?

NAD+ recycling consumes methyl groups. Chronic NMN supplementation without methyl donor
replenishment can strain the SAM cycle. TMG protects against that depletion and supports
homocysteine metabolism in the process.

Is this a replacement for NAD+ IV therapy?

This is an oral supplementation strategy. Different format, different cost profile, different use
case. Many users do both.

Customers usually bought these together:

Longevity Core

Aging is not one thing. Neither is the solution.

Why Most NAD+ Supplements Fall Flat

The story is consistent. Someone reads about NAD+ decline. They start an NMN or NR supplement. A month or two later, they cannot tell whether anything changed. They blame the molecule, the dose, or the brand.

The molecule is not the problem. NMN works. Multiple human trials confirm dose-dependent blood NAD+ elevation. The issue is that NAD+ does not function as an isolated input.

Producing NAD+ matters. Preserving it from enzymatic consumption matters. Activating the pathways that consume it for repair matters. Protecting the methylation cycle that recycling NAD+ depletes matters. Supporting the body's natural maintenance of senescent cells matters. Inducing the autophagy that maintains cellular cleanup matters. Defending the tissues where NAD+-dependent repair is most critical matters.

Seven nodes. Most products address one.

The Seven Nodes

Production

NMN converts directly to NAD+ via NMNAT enzymes. The 500 mg dose elevated blood NAD+ approximately 75 percent over placebo in published trials.

Preservation

CD38 is the enzyme that drives most age-related NAD+ decline. Its expression rises with age and inflammation. Apigenin supports healthy CD38 activity, slowing the enzymatic consumption of the NAD+ pool.

Activation

Sirtuins, particularly SIRT1, perform much of the cellular repair that NAD+ enables. SIRT1 also benefits from direct activation. Pterostilbene supports SIRT1 activity with approximately 80 percent oral bioavailability versus 30 percent for resveratrol.

Methylation Protection

NAD+ biosynthesis and recycling consume methyl groups. Without replenishment, the SAM cycle gets strained. TMG (trimethylglycine) donates methyl groups directly via the BHMT pathway, supporting both methylation capacity and homocysteine metabolism.

Senescent Cell Support

Senescent cells secrete inflammatory factors that upregulate CD38. Supporting the body's natural cellular maintenance processes addresses one of the upstream drivers of NAD+ decline. Quercefit phytosome quercetin delivers the bioavailability that standard quercetin lacks.

Autophagy

Cellular recycling declines with age. Damaged proteins, defective organelles, and debris accumulate. Spermidine induces autophagy through the eIF5A hypusination pathway. A 2024 Nature Cell Biology paper established it as an obligatory mediator of fasting-induced longevity across species.

Tissue Defense

The brain, heart, kidneys, and skeletal muscle mitochondria are most vulnerable to oxidative damage and most reliant on NAD+-dependent repair. L-Ergothioneine has a dedicated cellular transporter (OCTN1) that concentrates it specifically in these tissues.

The Formula

100% transparent formula showcasing each ingredient at its researched dose, because not all supplements are created equal. View Supplement Facts.
NMN, 500 mg

Nicotinamide mononucleotide. Direct NAD+ precursor that converts to NAD+ in a single enzymatic step via NMNAT enzymes.

NMN, 500 mg
Pterostilbene, 100 mg

The methylated analog of resveratrol with superior pharmacokinetics. About 80 percent oral bioavailability versus roughly 30 percent for resveratrol, plus a longer half-life because methoxy groups resist glucuronidation.

Pterostilbene, 100 mg
TMG (Betaine Anhydrous), 500 mg

Methyl donor at the 1:1 ratio with NMN that has become the standard pairing in longevity protocols.

TMG (Betaine Anhydrous), 500 mg
Quercefit (Phytosome Quercetin), 300 mg

Indena's phytosome formulation with sunflower lecithin. Up to 20x improved absorption over standard quercetin powder.

Quercefit (Phytosome Quercetin), 300 mg
Spermidine from Spermidine HCl (Yüth), 10 mg

A natural polyamine that induces autophagy. The Yüth branded form is high-purity spermidine HCl

Spermidine from Spermidine HCl (Yüth), 10 mg
Apigenin 98%, 50 mg

A flavone that supports healthy CD38 activity. The same dose used in Longevity Core for the same reason.

Apigenin 98%, 50 mg
L-Ergothioneine, 25 mg

A unique sulfur-containing amino acid that humans cannot synthesize.

L-Ergothioneine, 25 mg
NMN, 500 mg

Nicotinamide mononucleotide. Direct NAD+ precursor that converts to NAD+ in a single enzymatic step via NMNAT enzymes.

NMN, 500 mg
Pterostilbene, 100 mg

The methylated analog of resveratrol with superior pharmacokinetics. About 80 percent oral bioavailability versus roughly 30 percent for resveratrol, plus a longer half-life because methoxy groups resist glucuronidation.

Pterostilbene, 100 mg
TMG (Betaine Anhydrous), 500 mg

Methyl donor at the 1:1 ratio with NMN that has become the standard pairing in longevity protocols.

TMG (Betaine Anhydrous), 500 mg
Quercefit (Phytosome Quercetin), 300 mg

Indena's phytosome formulation with sunflower lecithin. Up to 20x improved absorption over standard quercetin powder.

Quercefit (Phytosome Quercetin), 300 mg
Spermidine from Spermidine HCl (Yüth), 10 mg

A natural polyamine that induces autophagy. The Yüth branded form is high-purity spermidine HCl

Spermidine from Spermidine HCl (Yüth), 10 mg
Apigenin 98%, 50 mg

A flavone that supports healthy CD38 activity. The same dose used in Longevity Core for the same reason.

Apigenin 98%, 50 mg
L-Ergothioneine, 25 mg

A unique sulfur-containing amino acid that humans cannot synthesize.

L-Ergothioneine, 25 mg
Good Value(s)
Never run out
Consistent use for better results
Delivered monthly
With flexible delivery options and easy anytime cancellation.
Free shipping
On all subscription orders, even if you need to pause or adjust.

CA PROP 65 WARNING: This product can expose you to chemicals including lead, which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Frequent Questions
Should I take Longevity Core or Longevity RESTORE first?

Both. Each addresses different biological mechanisms. They are designed to work together.

How long until I notice a difference?

Most NAD+ trials show measurable blood NAD+ elevation within 2 weeks and functional
improvements within 4 to 12 weeks of consistent daily use.

Why do both Core and RESTORE contain Apigenin?

CD38 modulation is relevant to both formulas. Core preserves the NAD+ that already exists.
RESTORE preserves the NAD+ that NMN is producing. Same ingredient, same dose, different
purpose in each system.

Why is TMG included?

NAD+ recycling consumes methyl groups. Chronic NMN supplementation without methyl donor
replenishment can strain the SAM cycle. TMG protects against that depletion and supports
homocysteine metabolism in the process.

Is this a replacement for NAD+ IV therapy?

This is an oral supplementation strategy. Different format, different cost profile, different use
case. Many users do both.