Nicotinamide mononucleotide. Direct NAD+ precursor that converts to NAD+ in a single enzymatic step via NMNAT enzymes. The 500 mg dose produced 41.7 uM blood NAD+ vs 23.8 uM in placebo in the published arterial stiffness RCT, representing approximately 75 percent elevation.

Who It Is For:

• Adults who tried single-ingredient NMN or NR products and want the complete system.
• Adults in their 40s and beyond addressing the NAD+ decline that becomes measurable in this decade.
• Anyone who wants NAD+ production paired with the six other interventions that determine whether higher NAD+ actually translates into cellular function.
  
  

The methylated analog of resveratrol with superior pharmacokinetics. About 80 percent oral bioavailability versus roughly 30 percent for resveratrol, plus a longer half-life because methoxy groups resist glucuronidation. Supports SIRT1 activity 1.86-fold versus 1.29-fold for resveratrol in head-to-head comparisons.


Who It Is For:

• Adults who tried single-ingredient NMN or NR products and want the complete system.
• Adults in their 40s and beyond addressing the NAD+ decline that becomes measurable in this decade.
• Anyone who wants NAD+ production paired with the six other interventions that determine whether higher NAD+ actually translates into cellular function.
  
  

Methyl donor at the 1:1 ratio with NMN that has become the standard pairing in longevity protocols. Donates methyl groups via the BHMT pathway, supporting methylation capacity and homocysteine metabolism.


Who It Is For:

• Adults who tried single-ingredient NMN or NR products and want the complete system.
• Adults in their 40s and beyond addressing the NAD+ decline that becomes measurable in this decade.
• Anyone who wants NAD+ production paired with the six other interventions that determine whether higher NAD+ actually translates into cellular function.
  
  

Indena's phytosome formulation with sunflower lecithin. Up to 20x improved absorption over standard quercetin powder. The phytosome technology is what makes 300 mg clinically meaningful. Without it, the same dose of unformulated quercetin would produce negligible plasma levels


Who It Is For:

• Adults who tried single-ingredient NMN or NR products and want the complete system.
• Adults in their 40s and beyond addressing the NAD+ decline that becomes measurable in this decade.
• Anyone who wants NAD+ production paired with the six other interventions that determine whether higher NAD+ actually translates into cellular function.

A natural polyamine that induces autophagy. The Yüth branded form is high-purity spermidine HCl. 10 mg approximately doubles typical dietary intake (4.8 to 17 mg/day from food sources).


Who It Is For:

• Adults who tried single-ingredient NMN or NR products and want the complete system.
• Adults in their 40s and beyond addressing the NAD+ decline that becomes measurable in this decade.
• Anyone who wants NAD+ production paired with the six other interventions that determine whether higher NAD+ actually translates into cellular function.
  
  

A flavone that supports healthy CD38 activity. The same dose used in Longevity Core for the same reason. CD38 inhibition is relevant whether you are preserving existing NAD+ or producing new NAD+ via NMN.


Who It Is For:

• Adults who tried single-ingredient NMN or NR products and want the complete system.
• Adults in their 40s and beyond addressing the NAD+ decline that becomes measurable in this decade.
• Anyone who wants NAD+ production paired with the six other interventions that determine whether higher NAD+ actually translates into cellular function.
  
  

A unique sulfur-containing amino acid that humans cannot synthesize. It has a dedicated transporter protein (OCTN1) that concentrates it in tissues under the highest oxidative stress: the brain, heart, kidneys, red blood cells, and skeletal muscle mitochondria. Proposed as a longevity vitamin by Dr. Bruce Ames at UC Berkeley.


Who It Is For:

• Adults who tried single-ingredient NMN or NR products and want the complete system.
• Adults in their 40s and beyond addressing the NAD+ decline that becomes measurable in this decade.
• Anyone who wants NAD+ production paired with the six other interventions that determine whether higher NAD+ actually translates into cellular function.