Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core

Longevity Core

Aging is not one thing. Neither is the solution.

$74.99
Why This Matters?

Rather than relying on unverified claims or hidden blends, Revive MD prioritizes evidence-based formulation, full label transparency, and third-party testing for every batch produced. Our products are formulated with clinically supported ingredients and tested by independent laboratories to confirm exact dosing, quality, and purity.

Clinically Studied Ingredients
Every ingredient in our formulas is selected because it’s supported by human research and traditional use, not hype or trends. You get meaningful nutrients, precise dosing, and thoughtful formulation for real health outcomes.
Transparent Dosing — No Proprietary Blends
Unlike many brands that hide doses in “proprietary blends,” Revive MD puts every ingredient and amount on the label. You know exactly what you take and why it’s included.
Third‑Party Tested for Purity & Accuracy
Unlike many brands that hide doses in “proprietary blends,” Revive MD puts every ingredient and amount on the label. You know exactly what you take and why it’s included.
Supports cellular health and healthy aging
Supports cellular health and healthy aging
Promotes recovery and whole-body resilience
Promotes recovery and whole-body resilience
Provides antioxidant support for long-term vitality
Provides antioxidant support for long-term vitality
Formulated for daily longevity and wellness support
Formulated for daily longevity and wellness support

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Customers usually bought these together:

Longevity Restore
Longevity Restore
NAD+ production is step one. There are six more.
Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core Longevity Core

CUSTOMERS USUALLY BOUGHT THESE TOGETHER:

Longevity Restore
Longevity Restore
NAD+ production is step one. There are six more.

Longevity Core

Aging is not one thing. Neither is the solution.

$74.99
GMP CERTIFIED
GMP CERTIFIED
THIRD-PARTY TESTED
THIRD-PARTY TESTED
PHYSICIAN FORMULATED
PHYSICIAN FORMULATED
Supports cellular health and healthy aging
Supports cellular health and healthy aging
Promotes recovery and whole-body resilience
Promotes recovery and whole-body resilience
Provides antioxidant support for long-term vitality
Provides antioxidant support for long-term vitality
Formulated for daily longevity and wellness support
Formulated for daily longevity and wellness support

Select Quantity:

-
+

Subscribe & Save

Verified Star Reviews
Longevity Core
ONE TIME PURCHASE
Subscribe & Save Save Up 15%

The Problem with Most Longevity Supplements

Two camps dominate the market. The first sells single-ingredient NAD+ precursors at high doses and hopes that one molecule moves the needle. The second sells kitchen-sink blends with 15 to 20 ingredients at sub-clinical doses, where the label looks impressive but nothing inside is dosed high enough to do real work.Longevity Core takes a different approach. Six ingredients, every dose at the level used in published research, working as one system.


What Is Actually Declining

Mitochondria are the organelles that produce energy inside every cell. As you age, they make that energy less efficiently. Membrane potential drops, reactive oxygen species climb, and ATP output falls, so cells spend more on upkeep and have less energy left for everything else. Mitochondrial decline is one of the most measurable parts of biological aging.

Why mitochondrial function declines with age

Two things happen at once. Existing mitochondria take on oxidative damage and lose output, and the body recycles the damaged ones more slowly than it should. Without enough turnover, worn-out mitochondria accumulate and pull down the energy capacity of the whole cell. Human muscle studies show mitochondrial energy output can fall by roughly half across the adult lifespan.

How to support mitochondrial health

Support works on three jobs. Clear out damaged mitochondria through mitophagy, build new ones through biogenesis, and keep the energy machinery running with the right cofactors. Longevity CORE maps six ingredients to those three jobs, dosed at the amounts used in the research, not token amounts.

The Three-Node Approach

Mitochondrial Quality Control

Damaged mitochondria need to be cleared (mitophagy) and replaced (biogenesis). The cell already has machinery for this. With age, both processes slow.

NAD+ Preservation

Producing NAD+ is one input. Preventing its destruction is the other. CD38 is the enzyme that drives most age-related NAD+ decline. It consumes NAD+ at a 97-to-1 ratio for every signaling molecule it produces.

Stress Buffering

Cortisol elevation accelerates mitochondrial damage, suppresses biogenesis, and increases CD38 expression. Without addressing the stress axis, the other interventions face constant pressure.

The Formula

100% transparent formula showcasing each ingredient at its researched dose, because not all supplements are created equal. View Supplement Facts.
Urolithin A, 500 mg

A postbiotic metabolite that activates mitophagy through the PINK1/Parkin pathway. Supports the body's natural process of clearing damaged mitochondria so the cell can prioritize healthy ones.

Urolithin A, 500 mg
PQQ, 15 mg

Pyrroloquinoline quinone disodium salt. Phosphorylates CREB at serine 133, activating the PGC-1α promoter that drives mitochondrial biogenesis.

PQQ, 15 mg
CoQ10 (Ubiquinone), 100 mg

The electron carrier embedded in the inner mitochondrial membrane. Endogenous CoQ10 production peaks around age 20 and declines steadily afterward.

CoQ10 (Ubiquinone), 100 mg
Apigenin 98%, 50 mg

A flavone that supports healthy CD38 activity, helping preserve the NAD+ pool from enzymatic consumption.

Apigenin 98%, 50 mg
Rhodiola rosea (3% rosavins, 1% salidrosides), 200 mg

The Arctic adaptogen with European Medicines Agency designation for stress-associated symptoms.

Rhodiola rosea (3% rosavins, 1% salidrosides), 200 mg
BioPerine (>95% piperine), 10 mg

A patented black pepper extract that supports the absorption of fat-soluble compounds (CoQ10) and polyphenols (apigenin, rhodiola).

BioPerine (>95% piperine), 10 mg
Urolithin A, 500 mg

A postbiotic metabolite that activates mitophagy through the PINK1/Parkin pathway. Supports the body's natural process of clearing damaged mitochondria so the cell can prioritize healthy ones.

Urolithin A, 500 mg
PQQ, 15 mg

Pyrroloquinoline quinone disodium salt. Phosphorylates CREB at serine 133, activating the PGC-1α promoter that drives mitochondrial biogenesis.

PQQ, 15 mg
CoQ10 (Ubiquinone), 100 mg

The electron carrier embedded in the inner mitochondrial membrane. Endogenous CoQ10 production peaks around age 20 and declines steadily afterward.

CoQ10 (Ubiquinone), 100 mg
Apigenin 98%, 50 mg

A flavone that supports healthy CD38 activity, helping preserve the NAD+ pool from enzymatic consumption.

Apigenin 98%, 50 mg
Rhodiola rosea (3% rosavins, 1% salidrosides), 200 mg

The Arctic adaptogen with European Medicines Agency designation for stress-associated symptoms.

Rhodiola rosea (3% rosavins, 1% salidrosides), 200 mg
BioPerine (>95% piperine), 10 mg

A patented black pepper extract that supports the absorption of fat-soluble compounds (CoQ10) and polyphenols (apigenin, rhodiola).

BioPerine (>95% piperine), 10 mg
Good Value(s)
Never run out
Consistent use for better results
Delivered monthly
With flexible delivery options and easy anytime cancellation.
Free shipping
On all subscription orders, even if you need to pause or adjust.

CA PROP 65 WARNING: This product can expose you to chemicals including lead, which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Frequent Questions
What is mitophagy?

What is mitophagy? Mitophagy is how cells identify and recycle damaged mitochondria. It slows with age, which lets worn-out mitochondria build up. Urolithin A is the most studied compound for supporting it.

What is the difference between PQQ and CoQ10?

They do different jobs. PQQ supports building new mitochondria. CoQ10 sits inside existing mitochondria and helps move electrons through the energy-production chain. Using both covers building and running

How much Urolithin A should you take?

Most human research uses 500 mg per day, the amount in each serving of Longevity CORE.